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4-[2-({6-chloro-3-[3-(4-chloro-benzyl)-5-phenyl-3H-imidazol-4-yl]-1H-indole-2-carbonyl}-amino)-ethyl]-piperazine-1-carboxylic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1067657-87-7

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1067657-87-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1067657-87-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,7,6,5 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1067657-87:
(9*1)+(8*0)+(7*6)+(6*7)+(5*6)+(4*5)+(3*7)+(2*8)+(1*7)=187
187 % 10 = 7
So 1067657-87-7 is a valid CAS Registry Number.

1067657-87-7Upstream product

1067657-87-7Relevant academic research and scientific papers

3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES

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Page/Page column 92-93, (2008/12/04)

The invention relates to 3-heterocyclyl indolyl compounds capable of inhibiting the interaction between p53, or variants thereof, and MDM2 and/or MDM4, or variants thereof, respectively, said compounds having the formula (I) wherein R1, R2, R3, R4, RA, Y and Y are as defined in the specification. Due to their activity, the compounds are useful in the treatment of various disorders and diseases mediated by the activity of MDM2 and/or MDM4, or variants thereof, such as inflammatory or proliferative diseases or in the protection of cells.

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