1067666-09-4

Basic information

• Product Name: 6-[(E)-2-(3,5-dimethoxyphenyl)-ethenyl]benzofuran-4-ol
• Synonyms: 6-[(E)-2-(3,5-dimethoxyphenyl)-ethenyl]benzofuran-4-ol
• CAS NO: 1067666-09-4
• Molecular Weight: 296.323
• Mol File: 1067666-09-4.mol

Chemical Properties

• CAS DataBase Reference: 6-[(E)-2-(3,5-dimethoxyphenyl)-ethenyl]benzofuran-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[(E)-2-(3,5-dimethoxyphenyl)-ethenyl]benzofuran-4-ol(1067666-09-4)
• EPA Substance Registry System: 6-[(E)-2-(3,5-dimethoxyphenyl)-ethenyl]benzofuran-4-ol(1067666-09-4)

Safety Data

• Hazardous Substances Data: 1067666-09-4(Hazardous Substances Data)

Relevant articles and documents

Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity

A novel class of combretastatins, modified at A-ring or both A- and B-rings, mainly by replacement with benzofuran or benzo[b]thiophene, were synthesized. The new heterocombretastatins showed good cytotoxic activity on BMEC and H-460 cell lines. The aminocombretastatin 9f potently inhibits cell growth of BMEC and combretastatin-resistant HT-29 cell lines, with potential interest to treat colon carcinoma. Heterocombretastatins 9a,b inhibit tubulin polymerization similarly to CA-4 by having a binding to colchicine site five times stronger.