106771-57-7 Usage
Molecular structure
The compound contains a benzimidazole ring with a thioether group attached to a 4-fluorophenyl ring, and an isoindole-1,3(2H)-dione moiety.
Biological activity
Potential pharmaceutical applications due to the presence of the isoindole-1,3(2H)-dione moiety, which is known for its biological activities.
Specific structure
The compound's specific structure and properties would need to be further studied to determine its potential uses.
Industry applications
Possible uses in the pharmaceutical, chemical, or other industries, based on its structure and properties.
Fluorine content
The presence of a fluorine atom in the 4-fluorophenyl ring may influence the compound's reactivity, stability, and pharmacokinetic properties.
Thioether group
The presence of a thioether group (S-C) may affect the compound's lipophilicity, metabolic stability, and potential for protein binding.
Aromatic rings
The presence of multiple aromatic rings may contribute to the compound's stability and potential for π-π stacking interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 106771-57-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,7,7 and 1 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 106771-57:
(8*1)+(7*0)+(6*6)+(5*7)+(4*7)+(3*1)+(2*5)+(1*7)=127
127 % 10 = 7
So 106771-57-7 is a valid CAS Registry Number.
106771-57-7Relevant academic research and scientific papers
Substituted 2-anilines as Potential Inhibitors of H+/K+ ATPase
Adelstein, Gilbert W.,Yen, Chung H.,Haack, Richard A.,Yu, Stella,Gullikson, Gary,et al.
, p. 1215 - 1220 (2007/10/02)
A series of substituted 2-anilines were synthesized as potential inhibitors of the acid secretory enzyme H+/K+ ATPase.Substitutions on the aniline nitrogen atom resulted in potent enzyme inhibition in vitro but weak activity in gastric fistula dogs.Electron-donating substituents on the aniline ring enhanced in vitro and in vivo potency relative to the unubstituted analogue.The potency showed a correlation to the calculated pKa of the aniline nitrogen atom.Substitutions on the aniline and benzimidazole rings did not further enhance potency.Di- and trisubstituted aniline derivatives were potent inhibitors of the enzyme system.The preferred combination of substituents were a methoxy group on the benzimidazole ring and a single alkyl group on the aniline ring.One such compound, 76, was an effective inhibitor of acid secretion in the dog and was selected for further pharmacological study.
