1067891-50-2Relevant academic research and scientific papers
Titanocene(III)-catalyzed conversion of N-(epoxyalkyl)anilines into indolines
MacIejewski, John P.,Wipf, Peter
, p. 92 - 119 (2011/06/20)
Densely substituted indolines and azaindolines can be obtained by the titanocene(III) chloride catalyzed reductive opening of N-(oxiran-2-ylmethyl) anilines. The reaction optimization, substrate scope, and limitations are discussed, and a mechanistic pathway for the epoxideopening rearrangement is proposed. ARKAT-USA, Inc.
Titanocene(III)-catalyzed formation of indolines and azaindolines
Wipf, Peter,Maciejewski, John P.
supporting information; experimental part, p. 4383 - 4386 (2009/05/30)
(Chemical Equation Presented) Reductive cyclization of epoxides tethered to substituted anilines and aminopyridines in the presence of 3 mol % of titanocene dichloride and stoichiometric manganese metal promotes a radical annulation to form 3,3-disubstituted indolines and azaindolines.
