1067892-75-4

Basic information

• Product Name: 2-methylthio-4-(morpholin-4-yl)-6-phenylethynyl-pyrimidine-5-carbaldehyde
• Synonyms: 2-methylthio-4-(morpholin-4-yl)-6-phenylethynyl-pyrimidine-5-carbaldehyde
• CAS NO: 1067892-75-4
• Molecular Weight: 339.418
• Mol File: 1067892-75-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-methylthio-4-(morpholin-4-yl)-6-phenylethynyl-pyrimidine-5-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methylthio-4-(morpholin-4-yl)-6-phenylethynyl-pyrimidine-5-carbaldehyde(1067892-75-4)
• EPA Substance Registry System: 2-methylthio-4-(morpholin-4-yl)-6-phenylethynyl-pyrimidine-5-carbaldehyde(1067892-75-4)

Safety Data

• Hazardous Substances Data: 1067892-75-4(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 587878-87-3 2-(methylthio)-4-chloro-6-morpholin-4-ylpyrimidine-5-carboxaldehyde 

Downstream Products

• 1067892-94-7 (7Z)-7-benzylidene-5-methoxy-2-methylthio-4-(morpholin-4-yl)-5,7-dihydrofuro[3,4-d]pyrimidine 
• 1416952-46-9 dimethyl [(7Z)-5,7-dihydro-2-methylthio-4-(4-morpholinyl)-7-(phenylmethylene)furo[3,4-d]pyrimidin-5-yl]phosphate 
• 1206805-14-2 5-butoxy-2-methylthio-4-morpholin-4-yl-7-phenyl-5H-pyrano[4,3-d]pyrimidine 
• 1206805-15-3 2-methylthio-4-morpholin-4-yl-7-phenyl-5-(prop-2-ynyloxy)-5H-pyrano[4,3-d]pyrimidine 
• 1206804-99-0 (7Z)-7-benzylidene-5-isopropoxy-2-methylthio-4-morpholin-4-yl-5,7-dihydrofuro[3,4-d]pyrimidine 
• 1206805-01-7 (7Z)-7-benzylidene-5-tert-butoxy-2-methylthio-4-morpholin-4-yl-5,7-dihydrofuro[3,4-d]pyrimidine 
• 1206804-95-6 (7Z)-7-benzylidene-5-ethoxy-2-methylthio-4-morpholin-4-yl-5,7-dihydrofuro[3,4-d]pyrimidine 
• 1206805-13-1 5-ethoxy-2-methylthio-4-morpholin-4-yl-7-phenyl-5H-pyrano[4,3-d]pyrimidine 
• 1206805-11-9 5-methoxy-2-methylthio-4-morpholin-4-yl-7-phenyl-5H-pyrano[4,3-d]pyrimidine 
• 1137439-95-2 6-methoxycarbonyl-2-methylthio-4-morpholino-7-phenylquinazoline 
• 1104638-73-4 N-{4-(Z)-2-[(tert-butylamino)-2-phenylvinyl]-2-(methylthio)-6-morpholin-1-ylpyrimidin-5-ylmethylene}-2-methylpropan-2-amine 
• 1104638-91-6 2-(methylthio)-4-morpholin-1-yl-7-phenylpyrido[4,3-d]pyrimidine 

Relevant articles and documents

The first tandem acetalization/5-exo-dig cyclization of 6-phenylethynylpyrimidine-5-carbaldehydes: Efficient synthesis of 5-alkoxy-(7Z)-7-benzylidene-5,7-dihydrofuro[3,4-d]pyrimidines

The first example of catalyst-free tandem acetalization/ 5-exo-dig cyclization reactions of 6-phenylethynylpyrimidine-5-carbaldehydes is presented. Efficient novel synthesis of 5,7-dihy-drofuro[3,4-d]pyrimidine core is described. Thieme Stuttgart.

Study on the cyclization of 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine: microwave versus thermal preparation of pyrido[4,3-d]pyrimidines

Thermal and microwave initiated cyclization of 2,4-disubstituted 6-arylethynylpyrimidine-5-carbaldehydes with tert-butylamine has been studied. A novel high-yielding preparation of 2,4-disubstituted 7-arylpyrido[4,3-d]pyrimidines has been developed. The i