106797-52-8Relevant academic research and scientific papers
Preparation method for 2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-acetone
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Paragraph 0014; 0016; 0019; 0022; 0025, (2017/03/08)
The invention provides a preparation method for a hydroxy-ketone photoinitiator, i.e., 2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-acetone. In tradition production processes, chlorine or liquid bromine is used as a halogenation reagent, and halogenation and hydrolysis are successively carried out so as to obtain a target product; however, chlorine is severely poisonous gas prone to leakage while liquid bromine is easily volatile liquid with strong toxicity and corrosivity and produces a great amount of acidic exhaust gas in the process of halogenation, which leads to production of a great amount of waste water in the process of aftertreatment. The preparation method provided by the invention avoids usage of chlorine or liquid bromine as the halogenation reagent and directly prepares the target product in one step by using a carbon tetrachloride process. The preparation method provided by the invention has the advantages that the amount of exhaust gas produced in the process of reaction is small; feeding and aftertreatment are simple to operate; the output of wastewater is low; product content reaches 99% or above; and production cost is low.
Highly efficient C-H hydroxylation of carbonyl compounds with oxygen under mild conditions
Liang, Yu-Feng,Jiao, Ning
supporting information, p. 548 - 552 (2014/01/23)
A transition-metal-free Cs2CO3-catalyzed α-hydroxylation of carbonyl compounds with O2 as the oxygen source is described. This reaction provides an efficient approach to tertiary α-hydroxycarbonyl compounds, which are highly valued chemicals and widely used in the chemical and pharmaceutical industry. The simple conditions and the use of molecular oxygen as both the oxidant and the oxygen source make this protocol very environmentally friendly and practical. This transformation is highly efficient and highly selective for tertiary C(sp3)-H bond cleavage. OH, so simple! A transition-metal-free Cs2CO 3-catalyzed α-hydroxylation of carbonyl compounds with O 2 provided a variety of tertiary α-hydroxycarbonyl compounds (see scheme; DMSO=dimethyl sulfoxide), which are widely used in the chemical and pharmaceutical industry. The simple conditions and the use of molecular oxygen as both the oxidant and the oxygen source make this protocol very efficient and practical.
Copolymerizable photoinitiators
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, (2008/06/13)
The invention relates to copolymerizable photoinitiators of the general formula I STR1 in which R1 and R2 are each H, C1 -C6 -alkyl or phenyl, R3 is H, C1 -C6 -alkyl, C1 -C6 -alkyl, C1 -C6 -alkanoyl or the group Z, R4 is H, halogen, C1 -C12 -alkyl, C1 -C12 -alkoxy, C1 -C12 -alkylthio or the group --X[(CH2 --CH2 --O)n --Z]m and X os O, S or N n is an integer from 0 to 4, m is the integer 1 for X=O and S or the integer 1 or 2 for X=N, Z is the group --CO--CR=CR'R" with R, R', R" each being H or CH3, always at least one of the R3 or R4 groups containing the group Z.
Photoinitiators for photopolymerization of unsaturated systems
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, (2008/06/13)
Compounds of the general formula I STR1 wherein Z is CR1 R2 (OR3) or phenyl, R1 being H, C1-6 -alkyl or phenyl, R2 being H, C1-6 -alkyl or C1-6 -alkoxy and R3 being H, C1-6 -alkyl or C1-6 -alkanoyl and Z' is Y--[(CH2)m --X]n --, X being CH2 or 0, Y being OH; COOH or SO3 H including the alkali metal, alkaline earth metal or ammonium salts thereof and also the salts thereof with organic nitrogen bases; or NRR' in which R and R' are in each case H, C1-20 -alkyl or C1-4 -hydroxyalkyl, if appropriate quaternized or in the form of the acid addition salts, and n and m each being the numbers 1-4, are excellently suitable as photoinitiators for the photopolymerization of ethylenically unsaturated compounds, in particular in aqueous systems.
