1068-42-4

Basic information

• Product Name: Aminoguanidinium sulphate
• Synonyms: AMINOGUANIDINE SULFATE;AMINO GUANIDINE SULPHATE;AMINOGUANIDINIUM SULFATE;aminoguanidinium sulphate;Guanylhydrazinesulfate
• CAS NO: 1068-42-4
• Molecular Formula: CH6N4.H2O4S
• Molecular Weight: 172.16
• EINECS: 213-945-0
• Product Categories: Pharmaceutical Intermediates
• Mol File: 1068-42-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 261.4ºC at 760 mmHg
• Flash Point: 111.9ºC
• Appearance: /
• Vapor Pressure: 0.0116mmHg at 25°C
• CAS DataBase Reference: Aminoguanidinium sulphate(CAS DataBase Reference)
• NIST Chemistry Reference: Aminoguanidinium sulphate(1068-42-4)
• EPA Substance Registry System: Aminoguanidinium sulphate(1068-42-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 1068-42-4(Hazardous Substances Data)

Usage

General Description

Aminoguanidinium sulphate is a chemical compound that contains aminoguanidine, a derivative of guanidine, and sulphate, an ionic compound. Aminoguanidine is a chemical compound with potential pharmacological applications, primarily as an anti-diabetic and anti-inflammatory agent. It has been studied for its potential to inhibit the formation of advanced glycation end products (AGEs), which are implicated in the progression of diabetes and related complications. Aminoguanidinium sulphate is commonly used in research laboratories as a reagent for analytical and biochemical applications, and as a precursor for the synthesis of other organic and medicinal compounds. It is important to handle aminoguanidinium sulphate with caution, as it is a known irritant and may cause skin and eye irritation upon contact.

InChI:InChI=1/2CH6N4.H2O4S/c2*2-1(3)5-4;1-5(2,3)4/h2*4H2,(H4,2,3,5);(H2,1,2,3,4)

Upstream product

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Downstream Products

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• 35607-27-3 5-(pyridin-3-yl)-2H-1,2,4-triazol-3-amine 
• 105445-19-0 5-(methoxymethyl)-4H-1,2,4-triazol-3-amine 
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• 79127-57-4 4,5-dihydroxy-4,5-dioxo-1H-pyrrolo{2,3-f}quinoline-2,7,9-tricarboxylic acid 
• 67962-54-3 2C₁₀H₁₄N₄O₂*H₂O₄S 
• 3916-03-8 1--3-diaethylmethylenamino-guanidin 
• 37634-08-5 C₁₂H₁₇N₅S 
• 37634-09-6 C₁₂H₁₇N₅S 
• 37634-21-2 C₁₁H₂₁N₅S 
• 3916-05-0 1--3-isopropylidenamino-guanidin 
• 37634-13-2 C₁₁H₁₄ClN₅S 

Relevant articles and documents

Crystal structures of mono-, Di-, and triaminoguanidinium sulfate, as well as azidoformamidinium sulfate: Important precursors for syntheses of nitrogen rich ionic vompounds

Bis(1-aminoguanidinium) sulfate monohydrate (AG2SO4 H2O, 1), bis(1,3-diamino-guanidinium sulfate (DAG2SO 4, 2), bis(1,3,5-triaminoguanidinium) sulfate dihydrate (TAG 2SO4 2 Hsub

Improved synthesis process for lamotrigine

The invention discloses an improved synthesis process for lamotrigine. The process comprises the following steps: (1) synthesizing 2,3-dichlorobenzoyl cyanide: adding 2,3-dichlorobenzoic acid and thionyl chloride into a reactor, carrying out depressurized evaporating to remove thionyl chloride after a reaction is completed, adding cuprous cyanide into the reactor, and filtering out solids after a reaction is completed, so as to obtain a 2,3-dichlorobenzoyl cyanide solution; (2) preparing a condensate: adding aminoguanidine carbonate and an entrainer into a reactor, dropwise adding concentrated sulfuric acid, distilling off the entrainer and water, carrying out suction filtration, enabling solids to enter a reaction bottle, carrying out depressurized pumping, then, adding the 2,3-dichlorobenzoyl cyanide solution obtained in the step (1) into the reaction bottle, cooling the reaction bottle to room temperature after a reaction is completed, and carrying out suction filtration, so as to obtain the condensate; and (3) preparing cyclics: adding liquid alkali into the condensate obtained in the step (2), and carrying out crystallizing, filtering, washing and baking after a reaction, thereby obtaining the lamotrigine. According to the improved synthesis process for the lamotrigine, the quality and yield of the product, i.e., the lamotrigine can be remarkably increased, and the yield reaches 90% or more.

PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS

The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.