106824-50-4

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 693-02-7 hex-1-yne 
• 106824-45-7 2-(hex-1-yn-1-yl)benzaldehyde 

Downstream Products

• 1344731-31-2 3-butyl-1-(4-tert-butylphenoxy)isoquinoline 
• 1589566-20-0 (Z)-1-(1-(3-benzylidene-1,3-dihydroisobenzofuran-1-yl)cyclopropyl)-3-butylisoquinoline 
• 7661-42-9 3-n-butylisoquinoline 
• 1381987-13-8 6-(4-bromophenyl)-11-butyl-5,6,9,10-tetrahydro-5,10-(azenometheno)benzo[8]annulen-7(8H)-one 

Relevant academic research and scientific papers

Efficient synthesis of isoquinoline derivatives via AgOTf/Cu(OTf) 2-cocatalyzed cyclization of 2-alkynyl benzaldoxime

An efficient, AgOTf and Cu(OTf)2 multicatalytic intramolecular cycloisomerization of 2-alkynylbenzaldoxime is reported. Isoquinoline N-oxides have been found to be deoxygenated to the corresponding quinolines in good yields in dimethylformamide/ dichloroethane (v/v 5:1) as solvent at 120 °C. Copyright Taylor & Francis Group, LLC.

CONDENSED HETEROAROMATIC RING SYSTEMS. XI. A FACILE SYNTHESIS OF ISOQUINOLINE N-OXIDES

Isoquinoline 2-oxides (5a-f) were obtained by the cyclization of 2-ethynylbenzaldehyde oxime (4a-f) under basic conditions.The starting compounds (4a-f) were easily synthesized by the palladium-catalyzed reaction of 2-bromobenzaldehydes (1 and 2) with terminal acetylenes, and subsequent oximation of the resulting 2-ethynylbenzaldehydes (3a-f).