106824-53-7Relevant academic research and scientific papers
CONDENSED HETEROAROMATIC RING SYSTEMS. XI. A FACILE SYNTHESIS OF ISOQUINOLINE N-OXIDES
Sakamoto, Takao,Kondo, Yoshinori,Miura, Norio,Hayashi, Kazuhiko,Yamanaka, Hiroshi
, p. 2311 - 2314 (2007/10/02)
Isoquinoline 2-oxides (5a-f) were obtained by the cyclization of 2-ethynylbenzaldehyde oxime (4a-f) under basic conditions.The starting compounds (4a-f) were easily synthesized by the palladium-catalyzed reaction of 2-bromobenzaldehydes (1 and 2) with terminal acetylenes, and subsequent oximation of the resulting 2-ethynylbenzaldehydes (3a-f).
