1068474-37-2Relevant academic research and scientific papers
Synthetic approaches to anti-inflammatory macrolactones of the oxacyclododecindione type
Tauber, Johannes,Rudolph, Kristina,Rohr, Markus,Erkel, Gerhard,Opatz, Till
, p. 3587 - 3608 (2015)
Abstract Various synthetic approaches to the oxacyclododecindione-type macrolactones, known for their potent anti-inflammatory activity, are presented. These include an attempted carbonylative ring closure, a hydroacylation route, and an approach by ring-
Total synthesis of (S)-(-)-curvularin: A ring-closing-metathesis-based construction of the macrocyclic framework
Mohapatra, Debendra K.,Rahaman, Hasibur,Pal, Rita,Gurjar, Mukund K.
scheme or table, p. 1801 - 1804 (2009/04/08)
A convergent, flexible, and efficient approach to the synthesis of curvularin is described. Key step is the high-yielding macrocyclic ring formation by ring-closing metathesis (RCM) using the Grubbs second-generation catalyst. Georg Thieme Verlag Stuttgar
