106848-48-0Relevant academic research and scientific papers
Azoles. Part 5. Metal-Halogen Exchange Reactions of Polybromoimidazoles
Iddon, Brian,Khan, Nazir
, p. 1445 - 1452 (2007/10/02)
1,2-Dilithiated imidazoles were prepared by treating 2-bromo-4,5-dichloro- and 2,4,5-tribromoimidazole with 2 equivalents of butyl-lithium and trapped with various electrophiles to give moderate yields of the 2-substituted 4,5-dihalogeno compounds (4)-(10
A CONVENIENT SYNTHESIS OF 4(5)-MONO-, 4,5-DI-, AND 2,4,5-TRI-SUBSTITUTED IMIDAZOLES
Iddon, Brian,Khan, Nazir
, p. 1635 - 1638 (2007/10/02)
A procedure is described for the stepwise introduction of substituents (hydrogen included) into the imidazole ring by FGI of the bromine atoms in 1-protected 2,4,5-tribromo-imidazoles in the order 2-5-4 using halogen-metal exchange techniques.
