1068599-72-3Relevant academic research and scientific papers
Copper-Photocatalyzed Hydroboration of Alkynes and Alkenes
Zhong, Mingbing,Gagné, Yohann,Hope, Taylor O.,Pannecoucke, Xavier,Frenette, Mathieu,Jubault, Philippe,Poisson, Thomas
, p. 14498 - 14503 (2021)
The photocatalytic hydroboration of alkenes and alkynes is reported. The use of newly-designed copper photocatalysts with B2Pin2 permits the formation a boryl radical, which is used for hydroboration of a large panel of alkenes and a
Basic CuCO3/ligand as a new catalyst for 'on water' borylation of Michael acceptors, alkenes and alkynes: Application to the efficient asymmetric synthesis of β-alcohol type sitagliptin side chain
Stavber, Gaj,Casar, Zdenko
, p. 159 - 165 (2013/05/09)
The efficient 'on water' β-borylation using bis(pinacolato)diboron agent was achieved with a newly developed catalytic system based on basic copper carbonate and various ligands. The catalytic system was used for β-borylation of various Michael acceptors,
?-BORATION OF ALKENE AND ALKYNE INTERMEDIATES
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Page/Page column 41, (2013/10/22)
The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-borated compounds can be used as intermediates in the synthesis pharmaceutically active agents such as sitagliptin.
?-boration of alkene and alkyne intermediates
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Paragraph 0102; 0103, (2013/10/22)
The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-borated compounds can be used as intermediates in the synthesis of pharmaceutically active agents such as Sitagliptin.
?-boration of alkene and alkyne intermediates
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Paragraph 0080; 0081, (2013/10/22)
The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-boated compounds can be used as intermediates in the synthesis of pharmaceutically active agents such as Sitagliptin.
Metal catalysed hydroboration of vinyl sulfides, sulfoxides, sulfones, and sulfonates
Webb, Jonathan D.,Harrison, Daniel J.,Norman, David W.,Blacquiere, Johanna M.,Vogels, Christopher M.,Decken, Andreas,Bates, Craig G.,Venkataraman,Baker, R. Thomas,Westcott, Stephen A.
, p. 91 - 100 (2008/10/09)
The hydroboration of phenyl vinyl sulfide with catecholborane (HBcat) and pinacolborane (HBpin) has been examined with a number of rhodium complexes, all of which proceed with excellent regiocontrol in favour of the branched product PhSCH(B(OR)2)CH3. The corresponding linear product can be obtained exclusively in reactions employing [Cp*IrCl2]2 and HBcat. Catalysed hydroborations of (E)-2-(p-toluenethio)styrene with HBcat using Rh(acac)(dppp) gave predominant formation of one product while reactions using HBpin afforded several products arising from a competing C-S bond cleavage (acac = acetylacetonato, dppp = 1,3-bis(diphenylphosphino)propane). Although reactions of phenyl vinyl sulfoxide were complicated by a competing deoxygenation reaction, hydroborations of phenyl vinyl sulfone using HBcat once again gave regioselective formation of either the branched or linear products, depending on the choice of catalyst used to effect this transformation. Catalysed hydroborations of phenyl vinyl sulfonate were less chemo- and regioselective, yielding hydrogenation and diboration products in addition to the two hydroboration product isomers.
