1068608-50-3

Upstream product

• 1004519-87-2 (R)-6-((S)-2-hydroxy-4-(4-hydroxyphenyl)butyl)-5,6-dihydropyran-2-one 
• 1068608-29-6 C₃₀H₅₄O₆Si₂ 

Downstream Products

• 1443115-30-7 (1S,5R,7S)-7-(2,4-dihydroxyphenethyl)-2,6-dioxabicyclo[3.3.1]nonan-3-one 

Relevant academic research and scientific papers

Structure elucidation of a dihydropyranone from Tapinanthus dodoneifolius

A new dihydropyranone, (R)-6-[(S)-2-hydroxy-4-(4-hydroxyphenyl)butyl]-5,6- dihydropyran-2-one (1), was isolated from Tapinanthus dodoneifolius. The structure was determined from spectroscopic and X-ray crystallographic analysis. Compound 1 (named dodonein

Natural product hybrid and its superacid synthesized analogues: Dodoneine and its derivatives show selective inhibition of carbonic anhydrase isoforms I, III, XIII and XIV

The natural product dodoneine (a dihydropyranone phenolic compound), extracted from African mistletoe Agelanthus dodoneifolius, has been investigated as inhibitor of several human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms. By using superacid chemistry

Stereoselective total synthesis of (+)-dodoneine

A total synthesis of the naturally occurring dihydropyranone dodoneine is reported. The combination of a highly catalytic enantioselective allylboration and a highly diastereoselective allylstannation was used for the stereoselective generation of the two stereogenic centers. The pyranone ring was created in two steps through generation of a Z-configured ,-unsaturated ester and lactonization via intramolecular transesterification. Georg Thieme Verlag Stuttgart.

First stereoselective total synthesis of (+)-dodoneine

The first stereoselective total synthesis of the natural product (+)-dodoneine is described involving a Crimmins aldol reaction and a Horner-Wadsworth-Emmons olefination as the key steps.