106872-27-9 Usage
Uses
Used in Pharmaceutical Industry:
2-CBZ-AMINO-4-PHENYLBUT-2-ENOIC ACID METHYL ESTER is used as an intermediate in the synthesis of pharmaceutical compounds for its ability to contribute to the formation of active pharmaceutical ingredients. Its role in the production of drugs is vital, as it aids in the creation of molecules with specific therapeutic properties.
Used as a Reagent in Organic Synthesis:
In the realm of organic chemistry, 2-CBZ-AMINO-4-PHENYLBUT-2-ENOIC ACID METHYL ESTER is utilized as a reagent, facilitating various chemical reactions that are essential in the preparation of complex organic molecules. Its versatility in organic synthesis makes it a valuable component in the development of new chemical entities and pharmaceuticals.
Used in the Preparation of Active Pharmaceutical Ingredients:
2-CBZ-AMINO-4-PHENYLBUT-2-ENOIC ACID METHYL ESTER is employed as a building block in the preparation of active pharmaceutical ingredients, contributing to the structural framework of drugs that address specific medical needs. Its presence in the synthesis process is instrumental in achieving the desired pharmacological effects of the final drug product.
Check Digit Verification of cas no
The CAS Registry Mumber 106872-27-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,8,7 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 106872-27:
(8*1)+(7*0)+(6*6)+(5*8)+(4*7)+(3*2)+(2*2)+(1*7)=129
129 % 10 = 9
So 106872-27-9 is a valid CAS Registry Number.
106872-27-9Relevant academic research and scientific papers
SYNTHESIS OF α-AMINO ACIDS WITH β,γ-UNSATURATED SIDE CHAINS
Castelhano, Arlindo L.,Horne, Stephen,Taylor, Gregg J.,Billedeau, Roland,Krantz, Allen
, p. 5451 - 5466 (2007/10/02)
α-Amino acids with allenyl, vinyl and acetylenic side chains can be synthesized using non-enolate based strategies.The ester enolate-Claisen rearrangement applied to propargylic esters of N-protected α-amino acids is of limited utility since only poor yields of allenic product are obtained with the N-Boc glycine esters, the system which give the most reproducible results.However, α-allenyl-α-amino acids that are fully functionalized on the α-carbon are available through the agency of 4-allenyl-2-phenyloxazolones 4 ( obtained from propargyl esters of N-benzoyl protected amino acids via cyclization and Claisen rearrangement ) provided that Meerwein's reagent is used to facilitate hydrolysis of the benzamide function in 5.A variety of α-substituted glycinates, including those with α-vinyl and α-acetylenic functions, can be prepared using a two step sequence involving condensation of the cationic glycine synthon 22 with various organomagnesium reagents, followed by hydrolysis.
