106877-19-4 Usage
General Description
3-Methoxy-2,6-bis(trifluoromethyl)aniline is a chemical compound with the molecular formula C9H7F6NO. It is a derivative of aniline, with two trifluoromethyl groups attached to the 2 and 6 positions and a methoxy group attached to the 3 position of the benzene ring. 3-methoxy-2,6-bis(trifluoromethyl)aniline is used in the synthesis of pharmaceuticals and agrochemicals, as well as in research and development. It is a versatile building block in organic synthesis, and its trifluoromethyl groups make it a valuable tool for introducing fluorine atoms into complex molecules. 3-Methoxy-2,6-bis(trifluoromethyl)aniline is also used as a reagent in the production of dyes, pigments, and other specialty chemicals. Due to its potential health and environmental hazards, proper handling and disposal procedures should be followed when working with 3-methoxy-2,6-bis(trifluoromethyl)aniline.
Check Digit Verification of cas no
The CAS Registry Mumber 106877-19-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,8,7 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 106877-19:
(8*1)+(7*0)+(6*6)+(5*8)+(4*7)+(3*7)+(2*1)+(1*9)=144
144 % 10 = 4
So 106877-19-4 is a valid CAS Registry Number.
106877-19-4Relevant academic research and scientific papers
Reactions of Trifluoromethyl Bromide and Related Halides: Part 10. Perfluoroalkylation of Aromatic Compounds induced by Sulphur Dioxide Radical Anion Precursors
Tordeux, Marc,Langlois, Bernard,Wakselman, Claude
, p. 2293 - 2299 (2007/10/02)
Perfluoroalkylation of electron-rich aromatic compounds with trifluoromethyl bromide, or long-chain perfluoroalkyl iodides, was performed in the presence of sodium dithionite or zinc-sulphur dioxide.This alkylation occurred at the ortho and para positions relative to the amino or hydroxy substitutent.Pyrroles were perfluoroalkylated regioselectively at the 2-position.This alkylation was interpreted as a radical aromatic substitution; the formation of the perfluoroalkyl radical can be induced by a single-electron transfer from sulphur dioxide radical anion to the perfluoroalkyl halide.
Perfluoroalkylation of Anilines in the Presence of Zinc and Sulphur Dioxide
Wakselman, Claude,Tordeux, Marc
, p. 1701 - 1703 (2007/10/02)
Arylamines are transformed into their ortho- and para-trifluoromethyl derivatives by the action of trifluoromethyl bromide under slight pressure in the presence of 0.15 equiv. of zinc and sulphur dioxide in dimethylformamide.
