106897-41-0Relevant articles and documents
Inhibition of Cryptosporidium parvum in vitro by 9-(alkylthio)acridine derivatives
Khalifa, Latifa,Rosales, Maria-Jose,Mascaro, Carmen,Karolak-Wojciechowska, Janina,Bsiri, Nadia,Brouant, Pierre,Barbe, Jacques
, p. 163 - 166 (2007/10/03)
The synthesis of several acridinic thioethers is described. Compounds prepared were tested in vitro as potential drugs against the opportunistic infection known as cryptosporidiosis. With a view to predict activity, the quantitative structure-activity relationships were investigated. Correlations between experimental data and either log P or pKa are discussed.