1069111-45-0Relevant academic research and scientific papers
Synthesis of a stable iminium salt and propellane derivatives
Nagase, Hiroshi,Yamamoto, Naoshi,Nemoto, Toru,Yoza, Kenji,Kamiya, Kenshu,Hirono, Shuichi,Momen, Shinobu,Izumimoto, Naoki,Hasebe, Ko,Mochizuki, Hidenori,Fujii, Hideaki
, p. 8093 - 8096 (2008/12/22)
(Chemical Equation Presented) The treatment of morphinan 1 with NaH and MsCl provided very stable iminium salt 7 possessing propellane skeleton. One of the synthesized iminium salts 7, isobutyl derivative 7b, was crystallized and its structure was determined by X-ray crystallography. The natural bond orbital analysis suggested that the stability of the iminium should result from the stereoelectronic effect (hyperconjugation) attributed to their own structures.
