106944-13-2 Usage
Uses
Used in Pharmaceutical Industry:
2-Bromothiophen-3-amine is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and bromine substituent allow for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromothiophen-3-amine serves as an essential building block for the creation of novel agrochemicals. Its reactivity and functional groups enable the design of effective pesticides and other agricultural chemicals that can improve crop protection and yield.
Used in Dye Industry:
2-Bromothiophen-3-amine is utilized as a precursor in the production of dyes. Its chemical properties allow for the synthesis of a wide range of dyes with different color characteristics, enhancing the colorfastness and performance of various textiles and materials.
Used as a Reagent in Organic Synthesis:
2-Bromothiophen-3-amine is employed as a reagent in the synthesis of other organic compounds. Its bromine atom can be easily replaced or modified, making it a valuable component in the preparation of various organic molecules for research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 106944-13-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,9,4 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 106944-13:
(8*1)+(7*0)+(6*6)+(5*9)+(4*4)+(3*4)+(2*1)+(1*3)=122
122 % 10 = 2
So 106944-13-2 is a valid CAS Registry Number.
106944-13-2Relevant academic research and scientific papers
Etude des proprietes enaminiques de l'amino-3 thiophene et du diamino-3,4 thiophene
Outurquin, Francis,Lerouge, Patrice,Paulmier, Claude
, p. 267 - 275 (2007/10/02)
In the preceding paper, access to secondary and tertiary amines derived from 3-aminothiophene 1a and 3,4-diaminothiophene 3a has been discussed (1).Our results concerning the enamine character of these thiophenic amines are presented here.Using acidic catalysis, α-deuteration of the amines 1a to 1d and α,α'-dideuteration of diamine 3a have been observed.The C-protonation of 1a explains the formation of the bis(thienyl-3)amine 5 through a transamination reaction.Bromination leads to the bromoamines 7a and 9a and α-phenylselenenylation to the phenylselenoamines 7b and 9b.The reactivity of ethyl oxomalonate toward the enamine carbons of 1a and 3a has been shown by the isolation of the aminohydroxydiesters 12 and 14.The adducts 16 and 17 have been observed in the reaction between amines 1 and ethyl pyruvate. 6-methyl 5-oxo 5H-thienopyrazine 19 is the result of the same reaction with the diamine 3a.The reductive acid-catalyzed C-alkylation of 1a and 3a, by means of an aldehyde or a ketone and two equivalents of selenophenol, allows access to 2-alkyl 3-aminothiophenes 22 and 2,5-dialkyl 3,4-diaminothiophenes 24 or to acetamides 23 and 25.
