106947-63-1

Basic information

• Product Name: 1-[4-(1-Oxy-piperidin-1-yl)-phenyl]-ethanone
• Synonyms: 1-[4-(1-Oxy-piperidin-1-yl)-phenyl]-ethanone
• CAS NO: 106947-63-1
• Molecular Weight: 219.283
• Mol File: 106947-63-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-(1-Oxy-piperidin-1-yl)-phenyl]-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(1-Oxy-piperidin-1-yl)-phenyl]-ethanone(106947-63-1)
• EPA Substance Registry System: 1-[4-(1-Oxy-piperidin-1-yl)-phenyl]-ethanone(106947-63-1)

Safety Data

• Hazardous Substances Data: 106947-63-1(Hazardous Substances Data)

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 110-89-4 piperidine 
• 10342-85-5 4-piperidinoacetophenone 

Downstream Products

• 116868-34-9 PtCl₂(CH₂CH₂)(C₅H₁₀NOC₆H₄COCH₃) 
• 116868-40-7 PtCl₂(CH₂CHC₆H₅)(C₅H₁₀NOC₆H₄COCH₃) 
• 106947-69-7 1-[4-(Piperidin-1-yloxy)-phenyl]-ethanone 

Relevant articles and documents

Studies of Tetriary Amine Oxides. 9. Thermal Rearrangement of 1-(4-Substituted-phenyl)piperidine N-Oxides to the Corresponding N-Hydroxylamines

(4-Substituted - phenyl)piperidine N-oxides undergo a thermal rearrangement to O-arylhydroxylamines.Electron withdrawing substituents are essential for the rearrangement and must be ortho or para relative to the N-O function.The reaction has been found to be first order in substrate when rates were measured in dioxane, and the activation parameters were calculated.The order of reactivity in this rearrangement is NO2 >> CN > COPh > COMe > COOEt > CONH2.The rates correlate very well with ?- constants and the ρ value was positive and large (+3.6) pointing to a highly po lar activated complex with an electron-rich reaction center.All results strongly support an intramolecular cyclic mechanism.