106967-74-2

Basic information

• Product Name: (3-methoxyphenoxy)acetyl chloride
• Synonyms: (3-methoxyphenoxy)acetyl chloride;acetyl chloride, (3-methoxyphenoxy)-;2-(3-methoxyphenoxy)acetyl chloride;2-(3-methoxyphenoxy)ethanoyl chloride
• CAS NO: 106967-74-2
• Molecular Formula: C₉H₉ClO₃
• Molecular Weight: 200.62
• Mol File: 106967-74-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-methoxyphenoxy)acetyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (3-methoxyphenoxy)acetyl chloride(106967-74-2)
• EPA Substance Registry System: (3-methoxyphenoxy)acetyl chloride(106967-74-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 106967-74-2(Hazardous Substances Data)

Usage

General Description

(3-Methoxyphenoxy)acetyl chloride is a chemical compound with the molecular formula C10H9ClO3. It is an acetyl chloride derivative with a 3-methoxyphenoxy group attached to the acetyl chloride moiety. (3-methoxyphenoxy)acetyl chloride is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is a highly reactive compound that is sensitive to moisture and should be handled with care. The (3-methoxyphenoxy)acetyl chloride can undergo various chemical reactions, including acylation, nucleophilic substitution, and esterification, making it a versatile building block in organic synthesis.

Upstream product

• 2088-24-6 3-methoxyphenoxyacetic acid 
• 81720-20-9 methyl (3-methoxyphenoxy)acetate 
• 150-19-6 O-methylresorcine 
• 82815-86-9 (3-methoxy-phenoxy)-acetic acid ethyl ester 

Downstream Products

• 106967-80-0 (Z)-2-[2-(3-Methoxy-phenoxy)-acetyl]-3-methylamino-but-2-enoic acid ethyl ester 
• 106967-90-2 3-(3-Methoxy-phenoxymethyl)-5-methyl-isoxazole-4-carboxylic acid 
• 106967-85-5 5-(3-Methoxy-phenoxymethyl)-3-methyl-isoxazole-4-carboxylic acid 
• 1196669-89-2 C₂₇H₃₄N₆O₆S 
• 1246091-34-8 O,O-dimethyl-1-(3-methoxyphenoxyacetoxy)-1-(2-chlorophenyl)methylphosphonate 
• 1151474-46-2 n-dodecyl 2-(3-methoxyphenoxy)acetate 
• 1151474-47-3 4-chlorophenyl 2-(3-methoxyphenoxy)acetate 
• 1170909-68-8 N-[3-(2-benzothiazolyl)-4,5,6,7-tetrahydro-6-methylthieno[2,3-c]pyridin-2-yl]-2-(3-methoxyphenoxy)acetamide 
• 1446338-13-1 N-[4-(3-methylbutoxy)-2-nitrophenyl]-2-(3-methoxyphenoxy)acetamide 
• 1446337-66-1 1-isobutyl-2-(3-methoxyphenoxymethyl)-6-(3-methylbutoxy)-1H-benzimidazole 
• 1446338-15-3 N-[2-(isobutylamino)-4-(3-methylbutoxy)phenyl]-2-(3-methoxyphenoxy)acetamide 
• 1446338-14-2 N-[2-amino-4-(3-methylbutoxy)phenyl]-2-(3-methoxyphenoxy)acetamide 
• 1446338-21-1 4-[2-(3-methoxyphenoxy)acetylamino]-3-nitrophenyl 2-(3-methoxyphenoxy)acetate 

Relevant articles and documents

Synthesis of new plant growth regulator: N-(Fatty acid) O-aryloxyacetyl ethanolamine

N-(Fatty acyl) O-aryloxyacetyl ethanolamines, prepared from N-acylethanolamine (NAE) and aryloxyacetic acid, were tested for plant growth regulating activity. Compared with N-stearoylethanolamine, most compounds exhibit improved plant growth stimulating activity. In particular, those with chlorine on aryl ring show better activity than 2,4-dichlorophenyloxyacetic acid in stimulating hypocotyls elongation of rape which indicates that chlorine on aryl ring appears significant. Moreover, these derivatives display improved solubility.

Design and Synthesis of Novel 4-Hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one Derivatives for Use as Herbicides and Evaluation of Their Mode of Action

In order to develop a novel herbicide containing the β-triketone motif, a series of 4-hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one derivatives were designed and synthesized. The bioassay results showed that compound II15 had good pre-emergent herbicidal activity even at a dosage of 187.5 g ha-1. Moreover, compound II15 showed a broader spectrum of weed control when compared with a commercial herbicide 2,4-dichlorophenoxyacetic acid (2,4-D), and displayed good crop safety to Triticum aestivum L. and Zea mays Linn. when applied at 375 g ha-1 under pre-emergence conditions, which indicated its great potential as a herbicide. More importantly, studying the molecular mode of action of compound II15 revealed that the novel triketone structure is a proherbicide of its corresponding phenoxyacetic acid auxin herbicide, which has a herbicidal mechanism similar to that of 2,4-D. The present work indicates that the 4-hydroxyl-3-(2-phenoxyacetyl)-pyran-2-one motif may be a potential lead structure for further development of novel auxin-type herbicides.

BENZIMIDAZOLE DERIVATIVES AS SELECTIVE BLOCKERS OF PERSISTENT SODIUM CURRENT

The present invention is directed to a compound of Formula (I) or a pharmaceutically acceptable salt thereof; wherein R, R1, R2, R3, R4, m, and n are as defined herein, to pharmaceutical compositions comprising said compound, and to methods of treating diseases or conditions mediated by elevated persistent sodium current, such as an ocular disorder, multiple sclerosis, seizure disorder, and chronic pain.