1070245-53-2Relevant academic research and scientific papers
Catalytic Asymmetric Chlorocyclization of 2-Vinylphenylcarbamates for Synthesis of 1,4-Dihydro-2H-3,1-benzoxazin-2-one Derivatives
Yu, Yan-Min,Huang, Ya-Nan,Deng, Jun
supporting information, p. 1224 - 1227 (2017/03/14)
A facile synthetic approach to a series of chiral 4-chloromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one derivatives has been described. This transformation is achieved through the catalytic asymmetric chlorocyclization of 2-vinylphenylcarbamates using a newly developed organocatalyst. Furthermore, the resulting products can be easily converted into diverse bioactive agents.
Synthesis of 1,4-dihydro-2H-3,1-benzoxazin-2-ones by hydriodic acid mediated cyclization of t-butyl 2-vinylphenylcarbamates
Kobayashi, Kazuhiro,Fukamachi, Shuhei,Konishi, Hisatoshi
experimental part, p. 2301 - 2307 (2011/04/16)
A two-step facile synthesis of 4,4-disubstituted 1,4-dihydro-2H-3,1- benzoxazin-2-ones starting from α-substituted 2-aminostyrenes is described. The method involves the hydriodic acid mediated cyclization of t-butyl 2-vinylphenylcarbamate derivatives, whi
