107036-57-7 Usage
Uses
Used in Antiviral Applications:
5-Bromo-2',3'-dideoxycytidine is used as an antiviral agent for its ability to inhibit the replication of viral DNA, making it a candidate for the treatment of various viral infections. It has shown promise in preclinical studies for its potential use against HIV, hepatitis B, and hepatitis C.
Used in Anticancer Applications:
In the field of oncology, 5-Bromo-2',3'-dideoxycytidine is used as an anticancer agent due to its capacity to impede the replication of cancerous cells. It has been investigated for its potential to treat a variety of cancers, leveraging its mechanism of action to disrupt the uncontrolled cell division characteristic of malignancies.
Used in Enhancing Chemotherapy Efficacy:
5-Bromo-2',3'-dideoxycytidine is also used to enhance the efficacy of traditional chemotherapeutic drugs. When combined with existing cancer treatments, it has the potential to improve therapeutic outcomes, particularly in cases where tumors have developed resistance to standard chemotherapy.
Used in Pharmaceutical Industry:
Within the pharmaceutical industry, 5-Bromo-2',3'-dideoxycytidine is utilized as a research compound for the development of new therapeutic agents targeting viral infections and cancer. Its unique properties and demonstrated effects in preclinical models make it a valuable asset in the search for novel treatments.
Overall, 5-Bromo-2',3'-dideoxycytidine is a versatile compound with applications in both antiviral and anticancer therapies, as well as in improving the effectiveness of existing treatments. Its ongoing development and research underscore its potential to contribute to the medical field in significant ways.
Check Digit Verification of cas no
The CAS Registry Mumber 107036-57-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,0,3 and 6 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 107036-57:
(8*1)+(7*0)+(6*7)+(5*0)+(4*3)+(3*6)+(2*5)+(1*7)=97
97 % 10 = 7
So 107036-57-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H12BrN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h3,5,7,14H,1-2,4H2,(H2,11,12,15)/t5-,7+/m0/s1
107036-57-7Relevant academic research and scientific papers
Determining DNA sequences by mass spectrometry
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, (2008/06/13)
This invention relates to the methods, apparatus, reagents and mixtures of reagents for sequencing natural or recombinant DNA and other polynucleotides. In particular, this invention relates to a method for sequencing polynucleotides based on mass spectrometry to determine which of the four bases (adenine, guanine, cytosine or thymine) is a component of the terminal nucleotide. In particular, the present invention relates to identifying the individual nucleotides by the mass of stable nuclide markers contained within either the dideoxynucleotides, the DNA primer, or the deoxynucleotide added to the primer. This invention is particularly useful in identifying specific DNA sequences in very small quantities in biological products produced by fermentation or other genetic engineering techniques. The invention is therefore useful in evaluating safety and other health concerns related to the presence of DNA in products resulting from genetic engineering techniques.
5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity
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, (2008/06/13)
5-substituted 2',3'-dideoxycytidine compounds and their monophosphates are disclosed which have been found to have potent activity against retroviruses. The 5-fluoro-and 5-aza-substituted 2',3'-dideoycytidine compounds have been found to be effective against HTLV-III/LAV virus.
Potent Anti-AIDS Drugs. 2',3'-Dideoxycytidine Analogues
Kim, Chong-Ho,Marquez, Victor E.,Broder, Samuel,Mitsuya, Hiroaki,Driscoll, John S.
, p. 862 - 866 (2007/10/02)
5-Substituted 2',3'-dideoxycytidine analogues have been synthesized and evaluated in vitro for their capabilities to protect T4+ lymphocytes from the cytopathic effects of the HTLV-III/LAV (HIV) virus, the causative agent of acquired immunodefi
