107071-85-2Relevant academic research and scientific papers
N-substituted diphenylpiperidines and antiobesity use thereof
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, (2008/06/13)
Compounds of the formula STR1 wherein R1 is STR2 the asterisk denotes the specific bonding orientation to the piperidine moiety; R2 is alkylene or --CO--(CH2)n -- wherein n is 0 to 11; R3 and R4, independently, are hydrogen, halogen or lower alkoxy; and HET is pyridinyl, pyrimidinyl or imidazolyl, and salts thereof with pharmaceutically acceptable acids, are described. The compounds of formula I exhibit insulin lowering activity and are useful as antiobesity agents.
