1070716-82-3Relevant academic research and scientific papers
An improved protocol for the Pd-catalyzed α-arylation of aldehydes with aryl halides
Martin, Ruben,Buchwald, Stephen L.
, p. 4561 - 4564 (2008)
(Chemical Equation Presented) An improved protocol for the Pd-catalyzed α-arylation of aldehydes with aryl halides has been developed. The new catalytic system allows for the coupling of an array of substrates including challenging electron-rich aryl bromides and less reactive aryl chlorides. The utility of this method has been demonstrated in a new total synthesis of (±)-sporochnol.
