1070770-85-2

Upstream product

• 1070770-82-9 2-(2-(2-amino-5-methylphenoxy)ethoxy)-5-methylbenzeneamine 
• 1070770-80-7 4-methyl-2-(2-(4-methyl-2-nitrophenoxy)ethoxy)-1-nitrobenzene 
• 1070770-78-3 1-(2-chloro-ethoxy)-4-methyl-2-nitro-benzene 
• 119-33-5 4-methyl-2-nitrophenol 
• 1070770-84-1 [(2-{2-[2-(bis-methoxycarbonylmethyl-amino)-5-methyl-phenoxy]-ethoxy}-5-methyl-phenyl)-methoxycarbonylmethyl-amino]-acetica cid methyl ester 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1070770-86-3 C₄₁H₄₀Cl₂N₂O₁₃ 
• 1070770-87-4 C₃₇H₃₂Cl₂N₂O₁₃ 
• 1070770-88-5 C₅₂H₅₂Cl₂N₂O₂₃ 

Relevant academic research and scientific papers

Fluorescent ion indicators and their applications

Fluorescent dyes useful for preparing fluorescent metal ion indicators, the fluorescent indicators themselves, and the use of the fluorescent indicators for the detection, discrimination and quantification of metal cations.

Synthesis of new BAPTA calcium chelators

A series of new 1,2-bis-(2-aminophenoxyethane) N,N,N',N'-tetraacetic acid (BAPTA) chelators were designed and synthesized to form novel and improved fluorescent indicators. Substituted 2-nitrophenol, acting as the material, reacted in five steps to give BAPTA-derived chelators. The Ca2+ affinity of BAPTA chelators could increase significantly by addition of electron-donating groups and decrease by electron-withdrawing groups. Compounds 3a-e were treated with iron powder instead of hydrogenation, obtaining a satisfying yield. The structures of all compounds were characterized by infrared, 1H NMR, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) spectra.