1070872-50-2Relevant academic research and scientific papers
Stereo- and Regioselective Addition of Arene to Alkyne Using Abnormal NHC Based Palladium Catalysts: Elucidating the Role of Trifluoroacetic Acid in Fujiwara Process
Hota, Pradip Kumar,Jose, Anex,Mandal, Swadhin K.
, p. 4422 - 4431 (2017)
Hydroarylation of alkyne was reported by Fujiwara nearly two decades back. Interestingly, this reaction does not proceed in the absence of trifluoroacetic acid; however, the exact role of TFA has not been unambiguously established, in particular with the
Highly efficient alkyne hydroarylation with chelating dicarbene palladium (II) and platinum(II) complexes
Biffis, Andrea,Tubaro, Cristina,Buscemi, Gabriella,Basato, Marino
scheme or table, p. 189 - 196 (2009/04/07)
We report on a novel reaction protocol for the coupling of arenes with alkynes (the Fujiwara reaction), yielding products of formal trans/hydroarylation of the triple bond. The protocol makes use of a chelating N-heterocyclic dicarbene palladium(II) compl
