1070878-79-3Relevant academic research and scientific papers
Continuous flow microfluidic chemistry: Synthesis of [18F]-3-fluoro-2-(4-((2-nitro-1h-imidazol-1-yl)methyl)-1h-1,2,3-Triazol-1-yl)propan-1-ol, [18F]F-HX4, a potent hypoxia agent
Akula, Murthy,Blevins, David,Kabalka, George
, p. 745 - 754 (2017/04/10)
The microfluidic synthesis of the promising hypoxia imaging agent [18F]-3-fluoro-2-(4-((2-nitro-1H-imidazol-1-yl)methyl)-1H-1,2,3-Triazol-1-yl)propan- 1-ol, [18F]F-HX4, was successfully accomplished using a commercial microfluidic system. A decay correcte
Nitro-Imidazole Hypoxia Imaging Agents
-
Page/Page column 15, (2009/01/23)
The present invention relates to novel radioactively labeled bioreducible tracers of Formula I useful for detecting hypoxic tumors or ischemic tissue in vivo. In one embodiment, the tracers consist of a 2-nitroimidazole moiety, a triazole, metabolically s
