107092-94-4Relevant academic research and scientific papers
REACTION D'OXIMATION DES CETONES IV. CONSTANTES D'EQUILIBRE DE FORMATION DES CARBINOLAMINES INTERMEDIAIRES: DETERMINATION ET EFFETS DE STRUCTURE
Lamaty, G.,Roque, J. P.,Natat, A.,Silou, T.
, p. 2657 - 2666 (2007/10/02)
The equilibrium constants of formation, K1, of carbinolamines resulting from the addition of hydroxylamine to 19 ketones, - 5 aliphatic, 5 aromatic and 9 cyclanic -, have been measured at 25 deg C in water/methanol 60/40 v/v.A general method of determination of K1 is described.The variations of equilibrium constant are discussed in terms of torsional and nonbonding steric effects which are the main factors of reactivity for saturated ketones.
