1070980-31-2Relevant academic research and scientific papers
Catalytic enantioselective trapping of an alcoholic oxonium ylide with aldehydes: RhII/ZrIV-co-catalyzed three-component reactions of aryl diazoacetates, benzyl alcohol, and aldehydes
Zhang, Xu,Huang, Haoxi,Guo, Xin,Guan, Xiaoyu,Yang, Liping,Hu, Wenhao
supporting information; experimental part, p. 6647 - 6649 (2009/03/12)
(Chemical Equation Presented) The right combination: A catalytic asymmetric multicomponent reaction has been developed in which two stereogenic carbon centers are constructed in a single step (see scheme; erythro/threo 90:10, up to 80% yield, 98% ee).This type of enantioselective three-component reaction generates α,β-dihydroxy acid derivatives in good yields and with excellent enantioselectivities. Bn =benzyl.
