107099-99-0

Basic information

• Product Name: 2,5-Dimethoxyphenylboronic acid
• Synonyms: 2,5-DIMETHOXYPHENYLBORONIC ACID,99+%;2,5-Dimethoxyphenylboronic Acid (contains varying amounts of Anhydride);2,5-Dimethoxyphenylboronic acid ,98%;2,5-Dimethoxyphenylboronic acid,97%;2,5-Dimethoxyphenylboronic acid, May contain varying amounts of anhydride, 97%;(2,5-dimethoxyphenyl)boronic acid(SALTDATA: FREE);AKOS BRN-0036;2,5-DIMETHOXYPHENYLBORONIC ACID
• CAS NO: 107099-99-0
• Molecular Formula: C₈H₁₁BO₄
• Molecular Weight: 181.98
• EINECS: -0
• Product Categories: BoronicAcids;Boric Acid;Boronic Acid;Alkoxy;Aryl;Organoborons;B (Classes of Boron Compounds);Boronic Acids;Boronic Acids;Boronic Acids and Derivatives;blocks
• Mol File: 107099-99-0.mol

Chemical Properties

• Melting Point: 95-98 °C(lit.)
• Boiling Point: 374.5 °C at 760 mmHg
• Flash Point: 180.3 °C
• Appearance: /solid
• Density: 1.19 g/cm³
• Vapor Pressure: 2.84E-06mmHg at 25°C
• Refractive Index: 1.517
• Storage Temp.: 0-6°C
• Solubility: soluble in Methanol
• PKA: 8.12±0.58(Predicted)
• BRN: 2969872
• CAS DataBase Reference: 2,5-Dimethoxyphenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dimethoxyphenylboronic acid(107099-99-0)
• EPA Substance Registry System: 2,5-Dimethoxyphenylboronic acid(107099-99-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26-36/37-36/37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 107099-99-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2,5-Dimethoxyphenylboronic acid is used as a reagent in the Suzuki reaction for the formation of carbon-carbon bonds. This reaction is a widely employed method in organic chemistry for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical industries.
Used in Pharmaceutical Industry:
2,5-Dimethoxyphenylboronic acid is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of new drugs with potential therapeutic applications.
Used in Environmental Applications:
2,5-Dimethoxyphenylboronic acid is used as a bacterial mutagen in environmental studies. It can help in understanding the effects of mutations on bacterial populations and their role in the ecosystem.
Used in Research and Development:
2,5-Dimethoxyphenylboronic acid is used as a research compound for studying its properties and potential applications in various fields, including material science, chemical engineering, and biotechnology.

InChI:InChI=1/C8H11BO4/c1-12-6-3-4-8(13-2)7(5-6)9(10)11/h3-5,10-11H,1-2H3

Upstream product

• 150-78-7 1,4-dimethoxybezene 
• 121-43-7 Trimethyl borate 
• 25245-34-5 1-bromo-2,5-dimethoxybenzene 
• 5419-55-6 Triisopropyl borate 
• 688-74-4 boric acid tributyl ester 
• 7732-18-5 water 
• 39175-16-1 2-lithio-1,4-dimethoxybenzene 

Downstream Products

• 39020-34-3 5,7-Dimethoxy-4-(2,5-dimethoxyphenyl)-2H-1-benzopyran-2-one 
• 190371-84-7 2',5'-Bis-(4-dodecyloxy-phenylethynyl)-2,5,2'',5''-tetramethoxy-[1,1';4',1'']terphenyl 
• 247586-32-9 2-(2,5-dimethoxy-phenyl)-[1,3,2]dioxaborinane 
• 478190-83-9 2',5'-bis(4-(N,N-dibutylamino)phenyl)ethynyl-2,2,5,5-tetramethoxy[1,1':4',1]terphenyl 
• 502961-29-7 6-(2',5'-dimethoxyphenyl)-2-pyridylcarboxyaldehyde 

Relevant articles and documents

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ORGANIC LIGHT-EMITTING DIODE HAVING LONG LIFESPAN, LOW VOLTAGE, AND HIGH EFFICIENCY PROPERTY

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Structures and properties of 6-aryl substituted tris(2-pyridylmethyl)-amine transition metal complexes

A series of metal(II) complexes of [6-(2′,5′-dimethoxyphenyl)-2-pyridylmethyl]bis(2-pyridylmethyl) amine (L) have been prepared. X-Ray crystal structures have been determined for L and its metal(II) chloride complexes for Mn, Fe, Co, Ni, Cu and Zn and the results compared. The preparation and crystal structure of the unusual carbonato-bridged copper-tetramer [Cu4(L)4(CO3)2][BF4] 4·5.2H2O is also described. The solution-state structures of the complexes are deduced from their physicochemical and spectroscopic properties. The Zn(II) complex, [ZnCl2(L)], shows inversion about the ligand amine group on the NMR timescale - results from a variable temperature NMR study are presented and allow estimation of the barrier to amine inversion as 56 ± 0.5 kJ mol1. Overall, it is found that the intramolecular steric interactions introduced by substitution of the tris(2-pyridylmethyl)amine (tpa)-skeleton by a single 6-aryl group result in significant changes to the structures and properties of the resulting metal complexes: in particular the aryl-substitution in L causes (i) a weaker ligand-field compared to tpa favouring high-spin complexes, (ii) a tendency toward lower coordination numbers, and (iii) hemilability in the Ni(II) and Cu(II) complexes - the aryl-substituted leg of the ligand (L) is coordinatively labile.

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