1071-31-4Relevant academic research and scientific papers
The cobalt-catalyzed cross-coupling reaction of alkyl halides with alkyl Grignard reagents: A new route to constructing quaternary carbon centers
Iwasaki, Takanori,Takagawa, Hiroaki,Okamoto, Kanako,Singh, Surya Prakash,Kuniyasu, Hitoshi,Kambe, Nobuaki
, p. 1583 - 1592 (2014/06/23)
The cross-coupling of alkyl (pseudo)halides with alkyl Grignard reagents is catalyzed efficiently by a cobalt(II) chloride-lithium iodide-1,3-diene catalytic system, which provides a new synthetic tool for constructing sp 3 carbon chains. This system is particularly useful for creating quaternary carbon centers via the use of tertiary alkyl Grignard reagents. Various functional groups including esters, amides and carbamates are well tolerated.
Propargyl Stabilisation Energy
Roth, Wolfgang R.,Hopf, Henning,Horn, Carina
, p. 1781 - 1796 (2007/10/02)
For the alkynyl-substituted olefines 1 - 14 activation parameters for the geometrical isomerisation have been determined in the gasphase by the single-pulse shoke-tube technique.By comparison of these barriers with the corresponding one of the isolated double bonds, each corrected by the steric energy contribution of the ground and transition state, a value of 7.8 +/- 1.3 kcal * mol-1 for the propargyl stabilisation energy (PrSE) has been derived. - Key Words: Resonance energy / Stabilisation energy / Propargyl resonance / Force field calculation / Intrinsic rotational barrier / Single pulse shock tube / Gasphase kinetics / Heats of hydrogenation
