107111-82-0Relevant academic research and scientific papers
Use of 2-alkenyl-3-(chloromethyl)oxiranes in the synthesis of 1,5-dien-3-ols
Servi, Sueleyman,Ahmedzade, Misir,Coskun, Mehmet,Cansiz, Ahmet
, p. 73 - 76 (2007/10/03)
The reaction of unsaturated chloromethyl oxiranes with magnesium in tetrahydrofuran or with metallic sodium in methanol leads to the corresponding -1,5-dien-3-ols.
NEW SIGMATROPIC SEQUENCES BASED ON THE -WITTIG REARRANGEMENT OF THE BIS ALLYLIC ETHER SYSTEM A GENERAL APPROACH TO REGIOCONTROLLED C-C BOND FORMATION OF ALLYLIC MOIETIES LEADING TO UNSATURATED CARBONYL COMPOUNDS
Mikami, Koichi,Kishi, Naoyuki,Nakai, Takeshi,Fujita, Yoshiji
, p. 2911 - 2918 (2007/10/02)
Four new sigmatropic sequences triggered by the regiocontrolled -Wittig rearrangement of unsymmetrical bis-allylic ethers (1) to the 1,5-dien-3-ols (2) are described, which provide unique, regiocontrolled methods for the synthesis of a wide variety of unsaturated carbonyl compounds possessing interesting molecular frameworks.The newly developed sequences include the -Wittig-Claisen, the tandem -Wittig-oxy-Cope, the tandem oxy-Cope-Claisen, and the tandem oxy-Cope-Cope sequences.
SEQUIENTIAL WITTIG AND CLAISEN REARRANGEMENT: A FACILE SYNTHETIC METHOD FOR (E,E)-4,7-ALKADIENALS AND -ALKADIENOIC ACIDS. A NEW FORMAL SYNTHESIS OF (+/-)-CERULENIN
Mikami, Koichi,Kishi, Naoyuki,Nakai, Takeshi
, p. 1721 - 1724 (2007/10/02)
The regioselective Wittig rearrangement of bis-allylic ethers followed by the Claisen rearrangement permits ready access to (E,E)-4,7-alkadienals and -alkadienoic acids.The versatility of the sigmatropic sequence is demonstrated within the context of
