107145-35-7Relevant academic research and scientific papers
A simple Schiff base platform: sensing of Al3+ ions in an aqueous medium
Dhivya, Rajasekaran,Gomathi, Asaithambi,Viswanathamurthi, Periasamy
, (2019)
Abstract: A simple Schiff base probe PADP ((1,2-phenylenebis(azanylylidene)) bis(methanylylidene))bis(3-(diethylamino)phenol) was synthesized from 4-(diethylamino)salicylaldehyde and o-phenylenediamine and has been characterized using analytical and spectral methods. The emission spectrum of PADP Schiff base shows notable enhancement in the emission intensity at 500?nm in the presence of Al3+ in MeOH-H2O (1:9 v/v). On the other hand, other relevant metal ions did not influence considerably the emission spectrum of PADP. The detection limit and binding constant (Kb) of PADP towards Al3+ were found to be 0.104?μM and 3.0?×?106?M?1 from the fluorescence titration experiments. The 1:1 binding stoichiometry was further determined by Job’s plot and ESI-MS spectroscopy. The MTT assay shows no or negligible toxic nature of probe and thus it was utilized in vitro cell imaging studies of Al3+ ions. The results show that the probe PADP could be useful to detect Al3+ in an aqueous medium. Graphic abstract: A simple?non-toxic turn-on fluorescence receptor (PADP)?was designed. The sensing performance of the receptor up to a micromolar concentration of Al3+ ions is reported in 50?mM HEPES buffer [pH 7.4; H2O: MeOH (9:1 v/v)]. The receptor was also utilized to detect?Al3+ ions in living cells.[Figure not available: see fulltext.].
