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1071504-73-8

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  • 10,11-Dihydro-5H-pyrido[2,3-c][2]benzazepine-10-carboxylic Acid Ethyl Ester

    Cas No: 1071504-73-8

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1071504-73-8 Usage

Chemical Properties

Brown Oil

Uses

Intermediate in the preparation of Mirtazapine Impurity C

Check Digit Verification of cas no

The CAS Registry Mumber 1071504-73-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,1,5,0 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1071504-73:
(9*1)+(8*0)+(7*7)+(6*1)+(5*5)+(4*0)+(3*4)+(2*7)+(1*3)=118
118 % 10 = 8
So 1071504-73-8 is a valid CAS Registry Number.

1071504-73-8Relevant articles and documents

A METHOD FOR THE PREPARATION OF AN ENANTIOMERICALLY PURE BENZAZEPINE

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Page/Page column 17-18, (2008/12/08)

The invention relates to a method for the preparation of a cyclic compound according to formula (III) comprising reacting a compound according to Formula (I) and a compound according to formula (II), wherein in Formula (I), R1, R2, R3 and R4 may be hydrogen or substituent groups comprising one or more carbon atoms and/or hetero-atoms, wherein R1, R2, R3 and R4 can be combined in aromatic or aliphatic ring structures, -Y is a ring element comprising 1-3 substituted or unsubstituted carbon atoms and/or heteroatoms in the ring and -R5 is hydrogen or a hydrocarbon substituent group comprising one or more carbon atoms and optionally one or more hetero atoms, and wherein in Formula (II), Z1 and Z2 are, leaving groups, X is a reactive functional hydrocarbon group for subsequent ring closure, comprising one or more carbon atoms and a reactive functional group and having a chain of between 1 to 6 atoms between the carbon atom attached to the central carbon atom of formula (II) and the reactive functional group and R8 is hydrogen or a hydrocarbon substituent different from X making the central carbon atom of formula II a chiral centre in Formula (III) and wherein reactive functional group X can be or can be extended to be compound of formula (IV) which can be ring closed to produce the polycyclic component of formula (V). More in particular, the invention relates to the preparation of mirtazapine precursors and mirtazapine preferably having a substantial enantiomeric excess.

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