1071550-12-3 Usage
General Description
1-(4-Methoxybenzyl)-5-nitro-1H-indazole is a chemical compound that belongs to the class of indazoles. It consists of a 1H-indazole core with a 1-(4-methoxybenzyl) group attached to the nitrogen atom and a nitro group at the 5-position of the indazole ring. 1-(4-Methoxybenzyl)-5-nitro-1H-indazole has various potential applications in pharmaceutical and agrochemical industries due to its structural features. It may possess biological activities such as antimicrobial, antifungal, or cytotoxic properties, making it a valuable molecule for drug discovery and development. Additionally, its nitro group can serve as a useful synthetic handle for further functionalization and derivatization to obtain compounds with improved properties or biological activity. Overall, 1-(4-Methoxybenzyl)-5-nitro-1H-indazole is a versatile chemical with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1071550-12-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,1,5,5 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1071550-12:
(9*1)+(8*0)+(7*7)+(6*1)+(5*5)+(4*5)+(3*0)+(2*1)+(1*2)=113
113 % 10 = 3
So 1071550-12-3 is a valid CAS Registry Number.
1071550-12-3Relevant articles and documents
Linker Variation and Structure-Activity Relationship Analyses of Carboxylic Acid-based Small Molecule STAT3 Inhibitors
Lopez-Tapia, Francisco,Brotherton-Pleiss, Christine,Yue, Peibin,Murakami, Heide,Costa Araujo, Ana Carolina,Reis Dos Santos, Bruna,Ichinotsubo, Erin,Rabkin, Anna,Shah, Raj,Lantz, Megan,Chen, Suzie,Tius, Marcus A.,Turkson, James
supporting information, p. 250 - 255 (2018/03/21)
The molecular determinants for the activities of the reported benzoic acid (SH4-54), salicylic acid (BP-1-102), and benzohydroxamic acid (SH5-07)-based STAT3 inhibitors were investigated to design optimized analogues. All three leads are based on an N-met
Indazoles: Regioselective protection and subsequent amine coupling reactions
Slade, David J.,Pelz, Nicholas F.,Bodnar, Wanda,Lampe, John W.,Watson, Paul S.
supporting information; experimental part, p. 6331 - 6334 (2009/12/26)
(Chemical Equation Presented) Indazoles are unselectively protected under strongly basic conditions to give a mixture at N-1 and N-2. Under mildly acidic conditions, regioselective protection at N-2 takes place. Thermodynamic conditions lead to regioselective protection at N-1. This trend applies to various substituted indazoles. Protected 5-bromoindazoles participate in Buchwald reactions with a range of amines to generate novel derivatives.
