107167-31-7

Basic information

• Product Name: lactivicin
• Synonyms: lactivicin;2-[4-(Acetylamino)-3-oxoisoxazolidin-2-yl]tetrahydro-5-oxo-2-furancarboxylic acid;2-Furancarboxylic acid, 2-4-(acetylaMino)-3-oxo-2-isoxazolidinyl]tetrahydro-5-oxo-
• CAS NO: 107167-31-7
• Molecular Formula: C10H12 N2 O7
• Molecular Weight: 272.21
• Mol File: 107167-31-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.52g/cm³
• Refractive Index: 1.555
• CAS DataBase Reference: lactivicin(CAS DataBase Reference)
• NIST Chemistry Reference: lactivicin(107167-31-7)
• EPA Substance Registry System: lactivicin(107167-31-7)

Safety Data

• Hazardous Substances Data: 107167-31-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12N2O7/c1-5(13)11-6-4-17-12(9(6)15)19-10(16)7-2-3-8(14)18-7/h6-7H,2-4H2,1H3,(H,11,13)

Upstream product

• 113194-69-7 lactivicin A 
• 113194-68-6 lactivicin B 

Downstream Products

• 113194-68-6 lactivicin B 
• 113194-69-7 lactivicin A 

Related news

Synthesis of lactivicin (cas 107167-31-7) analogues08/12/2019

Aza analogues of lactivicin (1), a recently discovered novel antibiotic, were prepared by an application of our earlier convenient synthesis of 1 and its derivatives. A 1-unsubstituted pyrazolidinone derivative bearing 2-aminothiazol-4-yl-(Z)-methoxyiminoacetyl group exhibited in vitro antibacte...detailed

Relevant articles and documents

CHEMISTRY OF A NEW ANTIBIOTIC: LACTIVICIN

A novel antibiotic, lactivicin (LTV), was isolated from the culture filtrates of two bacterial strains by various types of chromatography.LTV exists in aqueous solution as an equilibrium mixture of two epimers in a ratio of about 1:1.The chemical structure of LTV (C10H12N2O7) was determined to be 2-(4S-acetylamino-3-oxo-2-isoxazolidinyl)-5-oxo-tetrahydrofuran-2-carboxylic acid.The absolute configuration at the C-6 position was elucidated from the CD spectral data and X-ray crystallographic analysis of 4-amino-lactivinic acid obtained by the iminoether method.This compound is useful as a starting material for chemical modification.LTV showed antibacterial activity against Gram-positive and negative bacteria, susceptibility to β-lactamases, and affinity for penicillin-binding proteins.We therefore concluded that LTV is a novel skeleton antibiotic having β-lactam-like activities.