1071814-44-2

Basic information

• Product Name: 2-(1-methyl-1H-pyrazol-5-yl)acetic acid
• Synonyms: 2-(1-methyl-1H-pyrazol-5-yl)acetic acid;(1-methyl-1H-pyrazol-5-yl)acetic acid
• CAS NO: 1071814-44-2
• Molecular Formula: C₆H₈N₂O₂
• Molecular Weight: 140.13992
• Mol File: 1071814-44-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(1-methyl-1H-pyrazol-5-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-methyl-1H-pyrazol-5-yl)acetic acid(1071814-44-2)
• EPA Substance Registry System: 2-(1-methyl-1H-pyrazol-5-yl)acetic acid(1071814-44-2)

Safety Data

• Hazardous Substances Data: 1071814-44-2(Hazardous Substances Data)

Usage

Type of compound

Derivative of pyrazole

Contains

Carboxylic acid group

Uses

Synthesis of pharmaceuticals and agrochemicals

Potential biological activities

Anti-inflammatory and analgesic properties

Importance

Building block for more complex molecules in pharmaceutical and chemical industries.

Upstream product

• 82668-50-6 ethyl 2-(1H-pyrazol-3-yl)acetate 
• 74-88-4 methyl iodide 
• 102732-63-8 2-(1H-pyrazol-3-yl)acetic acid 
• 144677-14-5 2-(1H-pyrazol-3-yl)acetohydrazide 
• 5418-51-9 5-nitro-2-hydroxypyridine 
• 84547-61-5 (1-methyl-1H-pyrazol-5-yl)methanol 
• 84547-63-7 5-(chloromethyl)-1-methyl-1H-pyrazole 
• 27258-33-9 1-methyl-1H-pyrazole-5-carbaldehyde 
• 1071814-43-1 2-(1-methyl-1H-pyrazol-5-yl)acetonitrile 

Downstream Products

• 1071814-21-5 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-2-(1-methyl-1H-pyrazol-5-yl)acetamide 
• 1071814-22-6 2-(4-chloro-1-methyl-1H-pyrazol-5-yl)-N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}acetamide 
• 1071814-24-8 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-2-(4-fluoro-1-methyl-1H-pyrazol-5-yl)acetamide 
• 1071814-23-7 2-(4-bromo-1-methyl-1H-pyrazol-5-yl)-N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}acetamide 

Relevant articles and documents

BIARYL COMPOUND, PREPARATION METHOD AND USE THEREFOR

The present invention belongs to the technical field of chemical pharmaceuticals, and relates to a compound represented by general formula (I) or formula (II) and a preparation method thereof. The compounds are biaryl derivatives with RORγt activation activity. The biaryl derivatives disclosed in this invention can effectively activate the RORγt protein receptor, and thereby promote the differentiation of Th17 cells and increasing the production of IL-17, which can be used as an immune modulator for the treatment of various cancers or viral infection-related diseases.