1072-12-4

Usage

Uses

Used in Analytical and Industrial Processes:
Glyoxal dithiosemicarbazone is used as a chelating agent for metal ion detection and removal due to its ability to form stable complexes with a variety of metals.
Used in Medical and Cosmetic Formulations:
Glyoxal dithiosemicarbazone is used as an antioxidant and antimicrobial agent in medical and cosmetic formulations, leveraging its potential to protect against oxidative stress and inhibit microbial growth.
Used in Pharmaceutical Development:
Glyoxal dithiosemicarbazone is used as a potential candidate in the development of new drugs due to its studied antitumor and antiviral activities. Further research is needed to explore its full potential in drug development.
Used in Research:
Glyoxal dithiosemicarbazone is used in research to understand its biological and chemical properties, as well as to explore its potential applications in various fields.

InChI:InChI=1/C4H8N6S2/c5-3(11)9-7-1-2-8-10-4(6)12/h1-2H,(H3,5,9,11)(H3,6,10,12)/b7-1-,8-2-

Upstream product

• 79-19-6 thiosemicarbazide 
• 53629-29-1 1,3-diethyl-4,5-dihydroxyimidazolidin-2-one 
• 131543-46-9 Glyoxal 

Relevant academic research and scientific papers

IMAGING AGENTS

The present invention provides certain thiosemicarbazone metal complexes which have advantageous properties in medical imaging. The thiosemicarbazone metal complexes can be safely and easily produced in real time, administered quickly after production, readily cross the blood-brain barrier, and may utilize a number of different radionuclides.

Heteronuclear NMR Spectroscopic Investigations of Gallium Complexes of Substituted Thiosemicarbazones Including X-Ray Crystal Structure, a New Halogen Exchange Strategy, and 18F Radiolabelling

Five thiosemicarbazone ligands have been synthesized, and their coordination chemistry with gallium was investigated. The reaction of these thiosemicarbazones with gallium chloride in alcohol solutions in the presence of a base yielded the corresponding p

Unexpected Formation of Thioglycolurils Precursors

Unexpectedly, nitrosation of 5,7-dialkyl-3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazine-6-ones(thiones) with sodium nitrite in glacial AcOH led to 3,3′-bis(5,7-dialkyl-1-nitroso-6-oxo(thioxo)-1,4,4a,5,7,7a-hexahydroimidazo[4,5-e]-1,2,4-triazinyl)disulfides that decomposed spontaneously into 1,3-dialkyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-ones(thiones) in DMSO-d6 in the presence of water.

Identification of differential anti-neoplastic activity of copper bis(thiosemicarbazones) that is mediated by intracellular reactive oxygen species generation and lysosomal membrane permeabilization

Bis(thiosemicarbazones) and their copper (Cu) complexes possess unique anti-neoplastic properties. However, their mechanism of action remains unclear. We examined the structure-activity relationships of twelve bis(thiosemicarbazones) to elucidate factors

Unexpected formation of 4-alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1, 2,4-triazine-3(2H)-thiones from 1,3-dialkyl-4,5-bis-(4-alkylthiosemicarbazido) imidazolidin-2-ones in acidic medium

4-Alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1,2,4-triazine-3(2H) -thiones are obtained either by heating 1,3-dialkyl-4,5-bis-(4- alkylthiosemicarbazido)imidazolidin-2-ones in acidic medium or the reaction of 1,3-dialkyl-4,5-dihydroxyimidazolidin-2-on