1072018-68-8 Usage
General Description
3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide is a complex chemical compound that involves various functional groups and structural elements. 3,5-Dichloro-N-[[4-fluoro-1-[[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]methyl]-4-piperidinyl]methyl]Benzamide exhibits dichloro substitution on a benzamide core, along with piperidine and tetrahydro-2H-pyran moieties. The piperidine ring is linked to the benzamide group through fluorine and methyl groups. On the other hand, the tetrahydro-2H-pyran ring is anchored to the structure via a methyl group. This chemical is specified with "4S" stereochemistry, indicating the spatial arrangement of the atoms. Like other compounds, its specific properties and uses are largely determined by its molecular structure and are expected to be explored in the fields of pharmaceuticals, agrochemicals and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1072018-68-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,2,0,1 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1072018-68:
(9*1)+(8*0)+(7*7)+(6*2)+(5*0)+(4*1)+(3*8)+(2*6)+(1*8)=118
118 % 10 = 8
So 1072018-68-8 is a valid CAS Registry Number.
1072018-68-8Relevant articles and documents
Design, synthesis, and evaluation of a novel 4-aminomethyl-4- fluoropiperidine as a T-type Ca2+ channel antagonist
Shipe, William D.,Barrow, James C.,Yang, Zhi-Qiang,Lindsley, Craig W.,Yang, F. Vivien,Schlegel, Kelly-Ann S.,Shu, Youheng,Rittle, Kenneth E.,Bock, Mark G.,Hartman, George D.,Tang, Cuyue,Ballard, Jeanine E.,Kuo, Yuhsin,Adarayan, Emily D.,Prueksaritanont, Thomayant,Zrada, Matthew M.,Uebele, Victor N.,Nuss, Cindy E.,Connolly, Thomas M.,Doran, Scott M.,Fox, Steven V.,Kraus, Richard L.,Marino, Michael J.,Graufelds, Valerie Kuzmick,Vargas, Hugo M.,Bunting, Patricia B.,Hasbun-Manning, Martha,Evans, Rose M.,Koblan, Kenneth S.,Renger, John J.
scheme or table, p. 3692 - 3695 (2009/04/07)
The novel T-type antagonist (S)-5 has been prepared and evaluated in in vitro and in vivo assays for T-type calcium ion channel activity. Structural modification of the piperidine leads 1 and 2 afforded the fluorinated piperidine (S)-5, a potent and selec
