107203-05-4Relevant academic research and scientific papers
Visible-Light-Induced External Radical-Triggered Annulation to Access CF2-Containing Benzoxepine Derivatives
Xiang, Haoyue,Zhao, Qing-Lan,Xia, Peng-Ju,Xiao, Jun-An,Ye, Zhi-Peng,Xie, Xiong,Sheng, Huan,Chen, Xiao-Qing,Yang, Hua
, p. 1363 - 1366 (2018)
A facile and diversified synthesis of functionalized CF2-containing benzoxepine derivatives via photoredox catalysis was achieved in this work. This novel protocol features broad substrate scope, mild reaction conditions, operational simplicity, easy scale-up, and versatile derivatization, which would facilitate its practical and broad applications in the construction of valuable and synthetically challenging heterocycles.
Visible Light Promoted Chan-Lam Reaction and Cycloaddition to Prepare Chromeno[4,3-c]isoxazolidines in One-Pot Reaction
Huang, Bing-Qing,Ma, Xiao-Pan,Mo, Dong-Liang,Zhao, Jie,Zhu, Bin-Can
supporting information, p. 4575 - 4581 (2021/08/13)
A variety of chromeno[4,3-c]isoxazolidines were prepared in good yields through visible light promoted Chan-Lam reaction and [3+2] cycloaddition cascade reaction in one pot. Mechanistic studies showed that visible light promoted both Chan-Lam reaction and cycloaddition. The obtained products were converted to various useful chromenone derivatives. Moreover, the reaction was easily performed at gram scales with the purification of products without column chromatography and used to efficiently synthesize estrone-derived chromeno[4,3-c]isoxazolidine. (Figure presented.).
