1072147-18-2Relevant academic research and scientific papers
SMAC MIMETIC DIMERS AND TRIMERS USEFUL AS ANTI-CANCER AGENTS
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Page/Page column 114; 153-154, (2008/12/08)
The invention provides small molecule mimics of the SMAC peptide that are dimer-like or trimer-like compounds having two or three amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
