107223-68-7

Upstream product

• 72457-25-1 4-(4-methoxyphenyl)butanenitrile 
• 115415-99-1 3-(4-Acetyloxyphenyl)butansauereamid 
• 7021-11-6 4-(4-hydroxyphenyl)butanoic acid 
• 18093-74-8 4-(4-acetoxyphenyl)butyric acid 

Downstream Products

• 97581-96-9 4-[4-(4-Acetyl-3-hydroxy-2-propyl-benzyloxy)-phenyl]-butyronitrile 
• 97582-01-9 1-(2-Hydroxy-3-propyl-4-{4-[3-(1H-tetrazol-5-yl)-propyl]-phenoxymethyl}-phenyl)-ethanone 

Relevant academic research and scientific papers

Cyclic imino derivatives and pharmaceutical compositions containing them

The invention relates to cyclic imino compounds which have, inter alia, valuable pharmacological properties, especially inhibitory effects on cell aggregation, pharmaceutical compositions which contain these compounds and processes for preparing them.

Liquid Crystalline trans-4-(ω-Cyanalkyl)cyclohexylester and 4-(ω-Cyanalkyl)phenylesters

The synthesis of the title esters 1 and 2a-e (n = 0-3) and their mesomorphic properties are described.When the alkyl-spacer n between the polar CN-group and the cyclohexane ring of cyanalkyl-cyclohexylesters 1 is increased the difference of the clearing points between the phenylesters 2 and the cyclohexylesters 1 decreases to nearly zero.The reason of higher clearing temperatures of 2 is a dynamic conformational effect of ring inversion of cyclohexane in the ester 1 with two polar substituents at the ring.