1072263-18-3Relevant academic research and scientific papers
Double functionalization of N-Boc-3-(tosylmethyr)indole exploiting the activating properties of the tosyl group
Palmieri, Alessandro,Petrini, Marino,Shaikh, Rafik R.
scheme or table, p. 1845 - 1851 (2009/04/07)
The anion prepared from N-Boc-3-(tosylmethyl)indole using NaH in DMF can be readily functionalized by reaction with various electrophiles. The obtained sulfonyl indoles, upon removal of the N-protecting group, undergo nucleophilic attack via a vinylogous imino derivative, leading to branched 3-substituted indoles. Georg Thieme Verlag Stuttgart.
