107274-38-4Relevant academic research and scientific papers
"nok": A phytosterol-based amphiphile enabling transition-metal-catalyzed couplings in water at room temperature
Klumphu, Piyatida,Lipshutz, Bruce H.
, p. 888 - 900 (2014/03/21)
The third-generation designer amphiphile/surfactant, "Nok" (i.e., SPGS-550-M; β-sitosterol methoxypolyethyleneglycol succinate), soon to be commercially available from Aldrich, can be prepared in two steps using an abundant plant feedstock and β-sitosterol, together with succinic anhydride and PEG-550-M. Upon dissolution in water, it forms nanomicelles that serve as nanoreactors, which can be characterized by both cryo-TEM and dynamic light scattering analyses. Several transition-metal-catalyzed reactions have been run under micellar conditions to evaluate this surfactant relative to results obtained in nanoparticles composed of TPGS-750-M (i.e., a second-generation surfactant). It is shown that Nok usually affords yields that are, in general, as good or better than those typically obtained with TPGS-750-M, and yet is far less costly.
The Use of R3SiSnR'3 in Organic Synthesis. A Novel Palladium-Catalyzed Tandem Transmetalation-Cyclization Reaction
Mori, Miwako,Kaneta, Naotake,Shibasaki, Masakatsu
, p. 3486 - 3493 (2007/10/02)
The intramolecular coupling of vinyl triflates 12 with vinyl halides proceeded smoothly in the presence of Bu3SnSiMe3 (1a) and a palladium catalyst and gave cyclic products 13 via tandem intermolecular and intramolecular transmetalations.
