1072804-68-2Relevant academic research and scientific papers
Stereoselective α-aminoallylation of aldehydes with chiral tert -butanesulfinamides and allyl bromides
Gonzalez-Gomez, Jose C.,Medjahdi, Mohamed,Foubelo, Francisco,Yus, Miguel
scheme or table, p. 6308 - 6311 (2010/11/17)
Figure presented. The combination of an aldehyde, an allylic bromide, and tert-butanesulfinamide in the presence of indium metal and titanium tetraethoxide allows straightforward access to homoallylamine derivatives in high yields and stereoselectivities. Moreover, the synthetic utility of the enantioenriched homoallylamine derived from n-decanal was illustrated in a concise synthesis of (+)-isosolenopsin. In this context, similar homoallylamines has been recently used by other groups in the synthesis of naturally occurring alkaloids.
Stereoselective synthesis of azetidines and pyrrolidines from N-tert-butylsulfonyl(2-aminoalkyl)oxiranes
Medjahdi, Mohamed,Gonzalez-Gomez, Jose C.,Foubelo, Francisco,Yus, Miguel
supporting information; experimental part, p. 7859 - 7865 (2010/01/16)
(Chemical Equation Presented) Base-induced cyclization of enantiopure (2-aminoalkyl)oxiranes allowed the stereospecific formation of pyrrolidin-3-ols and/or 2-(hydroxymethyl)azetidines, depending on the reaction conditions. The oxidation of 2-(hydroxymeth
