1072809-90-5Relevant academic research and scientific papers
An Efficient Approach for 3,3-Disubstituted Oxindoles Synthesis: Aryl Iodine Catalyzed Intramolecular C-N Bond Oxidative Cross-Coupling
Wang, Yang,Yang, Mo,Sun, Yuan-Yuan,Wu, Zheng-Guang,Dai, Hong,Li, Shuhua
supporting information, p. 8750 - 8754 (2021/11/17)
Herein, we report the first intramolecular C-N bond formation of phenylpropanamide derivatives via organocatalytic oxidative reactions, affording 3,3-disubstituted oxindole derivatives with up to 99% yield. The high efficiency of this reaction is exemplified by the transition metal-free mild conditions and the ability to perform the reaction on a gram scale. Meanwhile, the DFT calculation of the catalytic oxidative transformation pathway has also been studied.
Copper-catalyzed cross-coupling of O -alkyl hydroxamates with aryl iodides
Kukosha, Tatyana,Trufilkina, Nadezhda,Belyakov, Sergey,Katkevics, Martins
supporting information; experimental part, p. 2413 - 2423 (2012/09/07)
N-Aryl-O-alkylhydroxamic acid derivatives were prepared by copper-catalyzed cross-coupling of hydroxamates with aryl iodides. The reaction conditions are compatible with standard hydroxy-protecting groups on the hydroxylamine moiety and are applicable to
Synthesis of β-, γ-, and δ-lactams via Pd(II)-catalyzed C-H activation reactions
Wasa, Masayuki,Yu, Jin-Quan
supporting information; experimental part, p. 14058 - 14059 (2009/03/11)
Pd(II)-catalyzed intramolecular amination of sp2 and sp3 C-H bonds are developed using a combination of CuCl2 and AgOAc as the oxidant. The reaction protocol tolerates the presence of a double bond in the substrates. This catalytic reaction provides practical access to a wide range of β-, γ-, and δ-lactams. Copyright
