1072812-35-1 Usage
General Description
3-Methyl-2-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1h-indole is a chemical compound with a molecular formula of C18H22BNO2. It is an indole derivative that contains a boron-containing heterocycle within its structure. 3-Methyl-2-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1h-indole is often used as a building block in organic synthesis and medicinal chemistry, due to its ability to participate in various chemical reactions and its potential for use in pharmaceutical research. Its boron-containing moiety makes it a useful reagent in Suzuki-Miyaura cross-coupling reactions, which are commonly used to form carbon-carbon bonds in organic molecules. 3-Methyl-2-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1h-indole’s unique structure and reactivity make it a valuable tool in the development of new drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1072812-35-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,2,8,1 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1072812-35:
(9*1)+(8*0)+(7*7)+(6*2)+(5*8)+(4*1)+(3*2)+(2*3)+(1*5)=131
131 % 10 = 1
So 1072812-35-1 is a valid CAS Registry Number.
1072812-35-1Relevant articles and documents
Harnessing C-H Borylation/Deborylation for Selective Deuteration, Synthesis of Boronate Esters, and Late Stage Functionalization
Kallepalli, Venkata A,Gore, Kristin A.,Shi, Feng,Sanchez, Luis,Chotana, Ghayoor A.,Miller, Susanne L.,Maleczka, Robert E.,Smith, Milton R.
, p. 8341 - 8353 (2015/09/02)
Ir-catalyzed deborylation can be used to selectively deuterate aromatic and heteroaromatic substrates. Combined with the selectivities of Ir-catalyzed C-H borylations, uniquely labeled compounds can be prepared. In addition, diborylation/deborylation reactions provide monoborylated regioisomers that complement those prepared by C-H borylation. Comparisons between Ir-catalyzed deborylations and Pd-catalyzed deborylations of diborylated indoles described by Movassaghi are made. The Ir-catalyzed process is more effective for deborylating aromatics and is generally more effective in the monodeborylation of diborylated thiophenes. These processes can be applied to complex molecules such as clopidogrel.
