1072817-13-0

Basic information

• Product Name: C₃₀H₃₆N₆O₆S₂
• CAS NO: 1072817-13-0
• Molecular Weight: 640.784
• Mol File: 1072817-13-0.mol

Chemical Properties

• CAS DataBase Reference: C₃₀H₃₆N₆O₆S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₀H₃₆N₆O₆S₂(1072817-13-0)
• EPA Substance Registry System: C₃₀H₃₆N₆O₆S₂(1072817-13-0)

Safety Data

• Hazardous Substances Data: 1072817-13-0(Hazardous Substances Data)

Relevant articles and documents

Efficient solid-phase synthesis of FK228 analogues as potent antitumoral agents

Novel structural analogues of a HDAC inhibitor FK228 have been synthesized by modifying the most synthetically challenging unit, (3S,4E)-3-hydroxy-7- mercaptoheptenoic acid, with simple isosteric substitutions. These changes did not alter the backbone structure from FK228 but enabled facile and rapid synthesis by using readily available starting materials and high-yielding reactions. FK228 analogues were examined for their antitumoral activity on a variety of human cancer cells and led to the identification of new potent compounds.