1072849-75-2Relevant academic research and scientific papers
Enantioselective Iridium-Catalyzed Ring Opening of Low-Activity Azabenzonorbornadienes with Amines
Luo, Ren Shi,Cheng, Gengjinsheng,Wei, Yifei,Deng, Rinuan,Huang, Miao,Liao, Jianhua
supporting information, p. 1652 - 1655 (2018/06/18)
An iridium catalyst (2.5 mol %) generated in situ from [Ir(coe)2Cl]2 and a nitrogen phosphorus ligand was efficient in the asymmetric ring-opening reactions of low-activity azabenzonorbornadiene with various aliphatic and aromatic amines, providing the corresponding chiral vicinal 1,2-diamine scaffolds in high yields (up to 98%) and excellent enantioselectivities (up to 97% ee). The synthetic utility of the transformation was demonstrated by performing a gram-scale reaction.
Iridium-catalyzed asymmetric ring-opening reactions of N-boc- azabenzonorbornadiene with secondary amine nucleophiles
Yang, Dingqiao,Long, Yuhua,Wang, Huan,Zhang, Zhenming
supporting information; experimental part, p. 4723 - 4726 (2009/05/31)
(Equation Presented) Iridium-catalyzed asymmetric ring-opening reactions of N-Boc-azabenzonorbornadiene with a number of secondary amines has been developed for the first time. The reaction gave 1,2-trans-diamine derivatives in moderate to good yields wit
