1072895-42-1

Basic information

• Product Name: 5-(2-methylbut-3-yn-2-yloxy)-2-phenylbenzofuran
• Synonyms: 5-(2-methylbut-3-yn-2-yloxy)-2-phenylbenzofuran
• CAS NO: 1072895-42-1
• Molecular Weight: 276.335
• Mol File: 1072895-42-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(2-methylbut-3-yn-2-yloxy)-2-phenylbenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-methylbut-3-yn-2-yloxy)-2-phenylbenzofuran(1072895-42-1)
• EPA Substance Registry System: 5-(2-methylbut-3-yn-2-yloxy)-2-phenylbenzofuran(1072895-42-1)

Safety Data

• Hazardous Substances Data: 1072895-42-1(Hazardous Substances Data)

Upstream product

• 1111-97-3 3-chloro-3-methylbut-1-yne 
• 7182-29-8 5-hydroxy-2-phenylbenzofuran 

Downstream Products

• 1072895-45-4 7,7-dimethyl-2-phenyl-7H-furo[3,2-f]chromene 

Relevant articles and documents

A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial

From the structure of 3,3-dimethyl-3H-benzofuro[3,2-f][1]-benzopyran, a selective in vitro inhibitor of mycobacterial growth, we have undertaken a structure-activity relationship investigation. We wish to report here our results on the use of [2+3] cycloadditions between 2-formylbenzoquinone and various enol derivatives to give various 4-formyl-5-hydroxy benzofurans. In the next step, an ytterbium triflate-catalysed reaction with 2-methylpropene allowed the preparation of various original furo[3,2-f]chromenes derivatives. Their biological evaluation on the growth of Mycobacterium smegmatis as well as Mycobacterium tuberculosis pointed out that some analogues were four times more active than the initial hit.